P-Hydroxy Anisole

Basic Info:

  • Chemical Synonym(s): p-Methoxyphenol; Leucobasal; Phenol, 4-methoxy-; hydroquinone methyl ether; P-Guaiacol;
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  • CAS Number: 150-76-5
  • Chemical Formula:


  • MSDS: Download


Melting point
56 °C
Boiling point
243 °C(lit.)
1.55 g/cm3
Clear colorless to pale yellow
Flash Point
Water Solubility
40 g/L (25 ºC)
Vapor Density
4.3 (vs air)
Vapor Pressure
<0.01 mm Hg ( 20 °C)
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P-Hydroxy Anisole is a phenolic compound found in many plants. It is a colorless or slightly yellowish liquid with a strong odor, and it has a molecular weight of 120.216 g/mol.

It has a melting point of -4°C and a boiling point of 155-160°C. It can be soluble in water, chloroform, benzene, acetone, etc. It can react with oxidizing agents to form esters of p-hydroxybenzoic acid. 

It has many applications, including as an antioxidant and an antimicrobial agent. It can also be used to make some dyes, perfumes, and flavorings. It can act as a medicine to fight against tumors and prevent the formation of other cancers caused.


P-Hydroxy Anisole is an antioxidant. It can be used as a medicine to fight against tumors and prevent the formation of other cancers caused by oxidative stress. It is a chemical that was used to treat cancer.

It inhibits DNA synthesis and may act as a radiosensitizer. It makes tumors more sensitive to radiation therapy, but it does not work for all types of tumors. 

It is also an antimicrobial agent to prevent food spoilage from bacteria, yeast, and mold. When added to packaging material, it can extend the shelf life of certain foods by up to five times.

It is used in perfumes and certain foods because it gives a strong aniseed flavor. For example, it can be found in some Bitter Almond flavored products, ice cream, baked goods, sauces, and alcoholic beverages.

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