Diethyl Ether | CAS 60-29-7
기본정보
| 재산 | 값 |
|---|---|
| CAS 번호 | 60-29-7 |
| IUPAC Name | 1,1'-Oxybisethane |
| 분자식 | C4H10O |
| 분자 무게 | 74.12 g/mol |
| 모습 | 무색, 투명한 액체 |
| 청정 (GC) | ≥ 99.5% |
| 밀도 (20℃) | 0.713–0.716 g/mL |
| 비점 | 34.4–34.7 °C |
| 인화점 | -45 ℃ |
| 굴절률 | 1.352–1.354 (20℃) |
| Peroxide content | ≤ 1 ppm (pharma grade) |
| Water content | ≤ 0.05% (KF) |
소개
디 에틸 에테르 (CAS 60-29-7) 무색이다, highly volatile organic compound — one of the oldest known synthetic chemicals. It is widely used as a polar aprotic solvent across pharmaceutical, chemical, and laboratory applications.
Key physical properties that make it invaluable:
- Exceptionally low boiling point (34.6℃): Easy removal from reaction mixtures by evaporation at room temperature
- Selective miscibility: Partially miscible with water (6.9 g/100 mL at 20°C), fully miscible with most organic solvents — ideal for liquid-liquid extraction
- High vapor pressure (440 mmHg at 20°C): Rapid evaporation for clean recovery of products
Sunchem works directly with GMP-certified manufacturers in Jiangsu and Shandong to supply pharmaceutical-grade and industrial-grade diethyl ether at competitive FOB prices.
주요 애플리케이션
제약 & API Manufacturing
- Extraction and purification of alkaloids, antibiotics, and APIs
- Reaction solvent for Grignard reactions, lithiation chemistry, and organometallic chemistry
- Crystallization solvent for pharmaceutical intermediates
- Formulation of topical preparations
실혐실 & Analytical
- Liquid-liquid extraction in analytical sample preparation
- Solvent for TLC and column chromatography
- Preparation of anhydrous reaction media (absolute ether)
- GC calibration reference
Industrial Applications
- Starting fluid for diesel/gasoline engines in cold climates
- Solvent for fats, 왁스, gums, 수지, and natural rubber
- Solvent for nitrocellulose lacquers and varnishes
- Perfume and flavor extraction (maceration)
안전 & Handling
⚠️ Extremely flammable liquid — Flash Point -45°C
- Vapors are heavier than air; can travel to ignition sources
- Forms explosive 과산화물 on prolonged storage/exposure to light — test before use if stored >6 months
- UN1155; Packing Group I; Hazard Class 3
- Store in amber containers with BHT inhibitor; keep tightly sealed
포장
- 실혐실: 2.5 엘 / 25 L amber glass bottles or metal cans (with BHT stabilizer)
- 산업용: 180 kg iron drums
자주하는 질문
큐: What is the difference between anhydrous and regular diethyl ether?
무수물 (absolute) ether has water ≤0.001% for moisture-sensitive reactions (예를 들어, Grignard). Regular grade (≥99.5%) has ≤0.05% water, suitable for extraction and general lab use.
큐: How do I prevent peroxide formation in stored diethyl ether?
Store in amber containers, keep tightly sealed, add BHT inhibitor, and test for peroxides before use if stored >6 months. Never evaporate to dryness without first testing for peroxides.
큐: Is pharmaceutical-grade diethyl ether available?
Yes — BP/USP/EP standard with peroxide ≤1 ppm, water ≤0.05%, full COA including GC purity, 밀도, and refractive index.
큐: Are there import restrictions?
Diethyl ether is controlled/monitored in some countries as a drug precursor. Most countries allow import for industrial/pharmaceutical use with end-use certificates.