Basic Info:

  • Chemical Synonym(s): ARMOL; METOL4; GENOL; ELON; Metol sulphate; 4-Methylamino-phenol,Sulfat;
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  • CAS Number: 55-55-0
  • Chemical Formula:


  • MSDS: Download


Boiling Point
262.7ºC at 760 mmHg
Melting Point
Flash Point
Refractive index
1.6510 (estimate)
Storage temp.
H2O: 50 mg/mL, clear
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P-methylaminophenol sulfate is a white or colorless crystal with an acridine-like odor. It can be dissolved in water, ethanol, and ether. It is toxic and carcinogenic, and irritative to the skin, eyes, and respiratory tract. 

It has many industrial applications, such as the manufacture of paints, coatings, and varnishes. It is used as a food additive to improve processed foods' taste, color, and odor.

In the agrochemical industry, it is used as an acidifier and alkalizer to control electrolytes in fertilizers. It is used as a photographic developer to neutralize the reducing properties of metals.

It is a metabolite of the antidepressant drug moclobemide, which may be responsible for some of its pharmacological effects. It can produce symptoms resembling serotonin syndrome in combination with serotonergic antidepressants such as SSRIs or SNRIs.


As a chemical material, P-Methylaminophenol Sulfate is used in the production of sulfuric acid for synthetic resins. It can also be used in papermaking to help control electrolytes and provide the required alkalinity.

It is used as a photographic developer and can be used as a co-catalyst for reductive cracking to increase product yields and shorten processing cycles. It acts as a coupling accelerator for phenolic resins and is used as a catalyst to manufacture sulfuric acid.

In addition to these, it is an important synthetic intermediate of pigment used as coatings resins, natural colors, dyestuffs, etc. In the food industry, it has been applied in the production of MSG and hydrolyzed soy protein.

It is a drug used in neuroscience research that acts as a potent agonist of group II and III metabotropic glutamate receptors (mGluR). mGluRs are considered promising therapeutic targets for treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 

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