Basic Info:

  • Chemical Synonym(s): L-Leucine; H-GLU-OH; GLUTACID; H-L-GLU-OH; Aciglut; Expand
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  • CAS Number: 61-90-5
  • Chemical Formula:


  • MSDS: Download


1.035 g/cm3
Boiling Point
225.8ºC at 760 mmHg
Melting Point
Flash Point
Water Solubility
22.4 g/L (20 C)
3297 | L-LEUCINE
5.5-6.5 (20g/l, H2O, 20℃)
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L-Leucine is an essential amino acid that consists of two other Amino Acids - L-Isoleucine and L-Valine.

It is not synthesized by the human body and must be ingested through diet. It is the most abundant free-form amino acid in muscle tissue, representing 35% of all amino acids.

It can find it naturally in food sources such as soy, red meat, and fish. A good source of L-Leucine is eggs and soy proteins.

L-Leucine is a white crystalline powder that has a strong, fishy odor and an acidic taste. It belongs to the alpha amino acids group, and it contains both L-isomer of Leucine and D-isomer of Isoleucine.


L-Leucine is a branched-chain amino acid that plays a building block role in muscle development.

It plays a crucial role in the complete synthesis of proteins that build muscle mass. Scientists believe that the building blocks of proteins are responsible for muscle growth and L-Leucine is a crucial component in this process.

In the body, L-Leucine is converted to L-Isoleucine and L-Valine. These three amino acids play a significant role in muscle metabolism and control protein synthesis. In terms of functions, L-Leucine has been found to improve glucose tolerance and utilization and decrease the risk of obesity.

Furthermore, L-Leucine may also be beneficial to patients with liver cirrhosis, as it can help regulate the metabolism of fat and proteins. Again, a growing body of research shows that L-Leucine can effectively improve athletic performance and recovery.

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