Hyaluronic Acid

Basic Info:

  • Chemical Synonym(s): Hyaluronic Acid Sodium Salt;
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  • CAS Number: 9004-61-9
  • Chemical Formula:


  • MSDS: Download


Storage temp.
H2O: 5 mg/mL, clear, colorless
Lyophilized Powder
Refractive Index
1.78 g/cm3
Boiling Point
1274.4ºC at 760 mmHg
Flash Point
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Hyaluronic Acid, also known as Hya, hyaluronan, HA, is a sugar derived from the connective tissues of animals. HA is produced by combining two modified sugars with the arrowhead enzyme (also called arginase). One of these sugars is ribose five phosphate (a component of DNA) and glucosamine six phosphates (produced during metabolism), while another sugar is dextran.

It helps to keep skin supple and youthful by forming a gel-like layer on top of the skin's surface that holds moisture. Hyaluronic Acid can be found throughout one's natural collagen and most notably within the synovial joints. It retains water, supports healthy weight loss over time by decreasing the metabolism of sugars and carbohydrates, assists with blood pressure management, and helps fight osteoarthritis pain.

It comprises an amino acid chain composed of glucosamine and N-acetylglucosamine, which are often short-term dietary supplements derived from refined sugarcane or soy protein products. Hydrolysis reactions during production yield two key ingredients: Glycosaminoglycan (GAG), Chondroitin Sulfate.


Hyaluronic Acid can be used to decrease the depth of wrinkles from facial expressions. A treatment that uses injectable hyaluronic Acid with Botox provides long-lasting results with little downtime.

Hyaluronic Acid also is effective in the elimination of eye puffiness and dark circles. It is rich in feeling and moisture, which reduces under-eye hollows, distended red veins beneath the eyelid skin surface, swollen capillaries beneath the lid skin surface and eyelid skin discharge by about 75%!

It also acts as a filler for line removal or contouring. It helps to lock moisture onto the skin by absorbing 200x its weight in water. It can be synergistic with alpha-hydroxy acids for treating enlarged pores, irregular texture, and dull-looking skin. It potent humectant that also helps to deliver other skincare ingredients deep into the skin's surface. It reduces the appearance of wrinkles around the eyes by up to 60% with daily use over eight weeks. As we age, our bodies produce less Hyaluronic Acid, leading to visible wrinkles and dryness.

The physical properties of hyaluronic Acid make it highly soluble in both hot and cold water. And best of all, no matter the temperature change throughout its lifespan and usage, there is never any risk that Hyaluronic Acid will separate from solution. Other hyaluronic Acid may be applied externally where needed, such as around the eyes or mouth, for an immediate plumping effect.

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