Basic Info:

  • Chemical Synonym(s): 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide; PANTHENOL,USP; PANTOTHENOL; DL-PANTOTHENYLOL
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  • CAS Number: 16485-10-2
  • Chemical Formula:
  • MSDS: Download


Melting point
66-69 °C (lit.)
Storage temp
Inert atmosphere,Room Temperature
Water Solubility
Soluble in water, ethanol, ether, chloroform, and propylene glycol
1.166 g/cm3
Boiling Point
483.6ºC at 760 mmHg
Flash Point
Refractive Index
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DL-Panthenol is a synthetically manufactured vitamin B5 derivative. This additive is also known as Vitamin B5, dexpanthenol, or pantothenic acid.

It is a white or yellowish crystalline powder with a slight odor. It is produced by the reaction between the amino acids and the carboxylic acids to produce dimethylaminoethanol or methoxy ethanol.

It has anti-inflammatory activity and has been used as an ingredient in drugs to treat inflammatory skin diseases and acne. DL-Panthenol is a member of the group of bioflavonoids. Panthenol is a water-soluble vitamin.

Its main function is the synthesis of collagen, the most common structural protein in animals, particularly in the dermis and the epidermis.


When it is used as a drug, DL-Panthenol is commonly used as a topical application. It is a useful addition in the fight against the signs of aging in the dermis and improving the state in case of eczema, acne, irritations and dermatitis.

In dermatology, studies have been conducted to treat age spots, wrinkles, scars and erythema, small wounds and irritations in the dermis.

In cosmetology, it has been used to improve the quality of the hair and the nails. The properties include being very effective in increasing hair growth, improving hair quality and preventing skin diseases.

This ingredient is also used to treat superficial peeling, is recommended in cases of ichthyosis and xerosis. In cosmetics, it is used as a moisturizer and as a preservative.

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