Valsartan

Basic Info:

  • Chemical Synonym(s): Valsratan; Tareg; DIOVAN; Valsartane; Valsartan API; N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine; (S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid; L-Valsartan; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; 3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid; Nisis;
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  • CAS Number: 137862-53-4
  • Chemical Formula:

    C24H29N5O3

  • MSDS: Download

Characteristics: 

Melting point
116-117°C
Boiling point
684.9±65.0 °C(Predicted)
Density
1.212±0.06 g/cm3(Predicted)
Storage temp.
2-8°C
Flash Point
368ºC
Refractive Index
1.586
Vapor Pressure
1.06E-19mmHg at 25°C
Merck
14,9916
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Introduction:

Valsartan is a drug that belongs to a class of drugs called angiotensin receptor blockers.

It is used to treat high blood pressure, heart failure, and diabetic nephropathy and reduce the risk of stroke, heart attack, and other problems in people with type 2 diabetes.

It does not lower blood pressure in people with normal blood pressure. Valsartan works in the body by blocking the action of a particular hormone called angiotensin II. This hormone is found in the body and certain foods.

Angiotensin II causes blood vessels to narrow. As a result, the heart has to work harder to pump blood through your body. Valsartan blocks the action of angiotensin II. As a result, blood vessels relax and open up. This lowers blood pressure and reduces the stress on the heart. 

Applications:

Valsartan, an angiotensin II receptor antagonist antihypertensive drug, is used to treat hypertension post-myocardial infarction patients with hypertension (hypertension) and diabetes mellitus (metabolic syndrome). , has a long-lasting and stable blood pressure-lowering effect and low toxic side effects.

It is also used in patients with heart failure, in combination with other drugs.

It has some efficacy in the treatment and prevention of Alzheimer's disease, although this study is only in the laboratory stage.

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