P-Chlorophenyl Isocyanate

Basic Info:

  • Chemical Synonym(s): Benzene, 1-chloro-4-isocyanato-; Isocyanic Acid 4-Chlorophenyl Ester; 4-Chlorophenyl isocyanate;
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  • CAS Number: 104-12-1
  • Chemical Formula:

    C7H4ClNO

  • MSDS: Download

Characteristics: 

Melting point
26-29 °C (lit.)
Boiling point
203-204 °C (lit.)
Density
1.2 g/mL at 25 °C (lit.)
Storage temp.
2-8°C
Flash Point
60ºC
Refractive Index
1.5618
Density
1.26
Vapor Pressure
0.226mmHg at 25°C
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Introduction:

P-Chlorophenyl Isocyanate is an organic compound that belongs to the class of amides. It is a colorless liquid at room temperature, and it has an ammonia-like smell, which can cause olfactory fatigue quickly.

It is also poisonous and should be handled with care. When inhaled or ingested in small quantities, it does not have significant health effects, but exposure to high concentrations may cause skin and eye irritation, headache, dizziness, nausea, and vomiting. It is also believed to be carcinogenic to humans. 

It has applications in medicine and pest control industries, including its use as an inhibitor of mast cell degranulation to treat allergies, asthma, etc. It is used as an intermediate in pesticides to control aphids, scale, etc.

It is used in the production of adhesives, foams, and plasticizer coatings. Furthermore, it is used in the manufacture of polyurethane foam insulation for automobiles, etc.

Applications:

P-Chlorophenyl Isocyanater has many applications. It can be used in organic syntheses because the cyanate group reacts with acrylates, crotonates, or styrene derivatives to give corresponding urethane groups. It is used to make pesticides, herbicides, and defoliants. It is also employed for protein extraction to produce serum albumin. 

In paint formulations, it is used as a solvent for plasticizers or other additives that provide weathering, scrubbing, and scratch resistance.

It has applications in the electroplating industry because it removes water from the photoresist layer. It prevents slippage when applying chemicals and plating, thus ensuring imaging quality by improving adhesion between the photoresist layer and the metal substrate.

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