Didanosine

Basic Info:

  • Chemical Synonym(s): bmy40900;ddino;nsc612049;2',3'-Dideoxy inosine(DDI);DDI, Didanosine;2.3-Dideoxy;2',3'-Dideoxy-D-inosine;DIDANOSINE / 2'',3''-DIDEOXYINOSINE
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  • CAS Number: 69655-05-6
  • Chemical Formula:

    C10H12N4O3

  • MSDS: Download

Characteristics: 

Melting point
193-195 °C
Alpha
D25 -26.3° (c = 10 in water)
Boiling point
193-195 C
Density
1.2917 (rough estimate)
Refractive index
-28 ° (C=0.34, H2O)
Pka
9.12(at 25℃)
Form
Powder
Color
White to Off-white
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We help you source Didanosine in China

Our Advantages:

Our company has a team of specialized pharmaceutical intermediates, and at the same time we have a wealth of plant resources, we know the reactions each plant excels at, know the waste and exhaust gases for each reaction, and understand the costs and methods of treatment. So, we can quickly match the most suitable plant for you From the material in the lab, to commercial production, we can help you get it fast. We divide the entire pharmaceutical intermediate production process into the following sections: 1. Laboratories develop routes 2. Inter test test 3. Large production shop trial production Every step we have a lot of experience and success stories

We have a 20+ year track record of working with suppliers in China and rating reports on them, and we keep our suppliers updated with the latest news so our customers can get the latest supplier reports. We know the market well and have early warning notifications on upstream raw material prices to help you build a stable supply chain.

When selecting suppliers, our procurement specialists will audit the qualification of suppliers, conduct thorough investigations such as field visits and sample testing, and make ratings to ensure the authenticity and legality of supplier information.

We have a long-term stable cooperation with GLP laboratories, encounter customer test results and supplier test results do not match the situation, we will commission a third party to test to ensure the accuracy, authenticity and reliability of the experimental results. In this way, we can effectively control the product quality problems.

We have a long-term cooperative warehouse and can follow up packaging and labeling according to safety regulations and customer requirements. In order to effectively prevent damage to the goods in transit, we have prepared various reinforcement measures and packaging solutions.

We have a number of international freight companies with whom we have long-standing cooperation, and we can choose several route options according to the customer's requirements. For more difficult or urgent orders, we will prepare several alternative solutions to ensure safe and timely delivery.

 

We promise to immediately and unconditionally exchange or return the goods if they have quality problems. Our employees who deal with after-sales issues have many years of international work experience and are familiar with various processes in multinational work, so they can communicate and deal with after-sales issues without any obstacles.

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Introduction:

Didanosine is a medication used to treat HIV and hepatitis B. It comes in tablets, capsules, and syrup forms. The drug slows down the growth of the virus in your body and helps your immune system work better.

The drug is not a cure for HIV infection and must be used with other antiretroviral drugs to keep HIV levels active in the blood. Didanosine is a synthetic purine nucleoside phosphorylated to a monophosphate.

It helps your immune system get stronger. It is a potent inhibitor of HIV-1 replication. It inhibits HIV reverse transcriptase by competing with dATP for incorporation into nascent DNA chains. It acts as a chain terminator. The half-life of didanosine is around 16 hours.

Applications:

Didanosine is an antiretroviral nucleoside reverse transcriptase inhibitor (NRTI), which slows the growth of the virus by preventing it from using human DNA as a genetic blueprint for replication.

The indications for the use of Didanosine include HIV infection: treatment of HIV-1 infection (AIDS) in combination with other antiretroviral agents to reduce the risk of disease progression and death Hepatitis B infection: Treatment of chronic hepatitis B infections in combination with interferon alfa and ribavirin.

But it should not use it in the treatment of children. It is used to treat HIV infections that have developed resistance to other drugs used to treat the infection. The drug is also used to treat HIV in patients who have failed to respond to other antiretroviral drugs.

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