Atazanavir

Atazanavir is a potent HIV protease inhibitor. It binds reversibly and selectively to the active site of HIV-1 aspartyl protease (HIV-1 PR), which is essential for viral replication.

It has been shown that atazanavir can inhibit replication of multi-drug resistant HIV strains in cell culture. It has a low impact on the lipid distribution of the patient, which is one of its properties.

It is not cross-resistant to other anti-HIV drugs. Its in vitro activity differs from non-peptide PIs such as nelfinavir, which was designed based on X-ray diffraction studies of enzyme-azapeptide complexes and had a C-2 symmetric chemical structure.

Atazanavir is a drug that contains azathioprine and tenofovir disoproxil fumarate. The component azathioprine reduces inflammation caused by infection and may help control symptoms.

Tenofovir prevents other HIV viruses from reproducing themselves, making them less likely to cause an infection. It is used with other medications to treat HIV. It can also use it to treat hepatitis B.

It works in the body by stopping HIV from multiplying in your body and preventing it from attaching to and entering cells in your body. The most common side effects include stomach pain; diarrhea; 吐き気; vomiting, tiredness; headache; and trouble sleeping.